Human Sera
Cayman Chemical SInapaldehyde 100mg
A phenylpropanoid with diverse biological activities; an inhibitor of FTase (IC50 = 23.99 µM); inhibits TNF-α-induced NF-κB transcriptional activity in a reporter assay using HepG2 cells (IC50 = 13.25 µM); reduces LPS-induced NO production in RAW 264.7 cells (IC50 = 5.92 µM); scavenges DPPH and ABTS radicals in cell-free assays (IC50s = 83.02 and 43.15 µM, respectively); active against Gram-positive and Gram-negative bacteria (MICs = 64-128 UG/ml); inhibits α-glucosidase (IC50 = 98.81 µM)
Cayman Chemical PropentofylIn 50mg
A xanthine derivative and neuroprotective agent; increases NGF production in primary mouse astroglia maximally at 1.11 mM; reduces Aβ42-induced cell death in primary rat hippocampal neurons at 20 UG/ml; reduces infarct volume in a rat model of ischemic brain damage induced by permanent MCAO when administered following MCAO as an i.v. infusion at 0.01, 0.05, and 0.1 mg/kg per minute; inhibits cAMP phosphodiesterases, is an antagonist of adenosine A1 and A2 receptors, and binds to adenosine transporters
Cayman Chemical HArgGlyAspCysOHtrIfluo 50mg
An RGD-containing tetrapeptide; inhibits the binding of fibrinogen to endothelial cells and ADP-stimulated platelets (IC50s = 320 and 35 µM, respectively); implantation of titanium rods coated with H-Arg-Gly-Asp-Cys-OH increases bone formation in rat femurs; has been conjugated to polyethylenimine to improve gene transfection efficiency
Cayman Chemical MethyclothIazIde 50mg
A thiazide diuretic; inhibits norepinephrine- and vasopressin-induced contractions of aortic rings isolated from spontaneously hypertensive rats at a concentration of 100 μM; reduces salt-induced increases in blood pressure in salt-sensitive but not salt-resistant rats without affecting body weight or heart rate
Cayman Chemical TrIacontnoIc AcId 100mg
A very long-chain saturated fatty acid; a component of D-003
Cayman Chemical NorepInphrInbItartrat 100mg
A natural neurotransmitter and hormone that acts as an agonist of adrenergic receptors (Ki values are 330, 56, and 740 nM for α1, α2, and β1 adrenoceptors, respectively)
Cayman Chemical CarbetapentncItrate 100mg
A σ1 receptor agonist (Ki = 10.4 nM); inhibits citric acid-induced cough in guinea pigs from 1-5 mg/kg; reduces the number of seizures, mortality, and hippocampal neuronal cell death in a rat model of kainate-induced seizures at 12.5 and 25 mg/kg
Cayman Chemical ArachIdonyl GlycIn 50mg
Produced endogenously via oxidation of AEA, or by transacylation of arachidonoyl CoA; has analgesic activities in whole animal experiments, yet is a very poor ligand for the CB1 receptor
Cayman Chemical N 8ZHeptadecen1ylO 3p 100mg
A synthetic macamide that irreversibly inhibits FAAH with an IC50 value of 0.153 µM
Cayman Chemical MyclobutnIl 100mg
An analytical reference standard categorized as a triazole fungicide; found as a contaminant in concentrated Cannabis extracts from the California medical Cannabis market; intended for research and forensic applications
Cayman Chemical ScutelareIn 50mg
A flavone; has antioxidant activity in a TRAP assay at 1 μg/ml; inhibits sucrose hydrolysis by rat intestinal α-glucosidase and ATPase activity of the SARS coronavirus helicase nsP13 (IC50s = 12 and 0.86 μM, respectively); decreases LPS-induced NO release and iNOS and TNF-α mRNA expression in RAW 264.7 macrophages at 50 μM; decreases tumor weight and volume in an HT-1080 human fibrosarcoma mouse xenograft model at 0.5 μg/g
Cayman Chemical PTI-125hydrochlorIde 100mg
A purported binding agent of filamin A; the data regarding PTI-125 have prompted expressions of concern by the journals in which the data were published
Cayman Chemical DPTA Nonate 50mg
A NO donor with a half-life of three hours at 37°C, pH 7.4; liberates two moles of NO per mole of parent compound
Cayman Chemical IsoprInosIn 50mg
A complex of acetaminobenzoic acid, dimethylaminoisopropanol, and inosine in a 3:3:1 ratio; has a number of immunomodulatory effects, including inducing T-lymphocyte differentiation, augmenting macrophage and NK cell functions, and stimulating IL-2 production; shows antiviral activity
Cayman Chemical GunthIdInsulfate 100mg
A peripherally acting, antihypertensive compound that competes with norepinephrine for transport into presynaptic terminals of adrenergic neurons by the norepinephrine transporter, reducing the release of norepinephrine in response to action potentials